FERMA548762

ARFGAP1 Monoclonal Antibody (1C4E2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA548762-Each-of-1 In Stock ₹ 43,565.50

FERMA548762 - Each of 1

₹ 43,565.50

In Stock

Quantity

1

Base Price: ₹ 43,565.50

GST (18%): ₹ 7,841.79

Total Price: ₹ 51,407.29

Antigen

ARFGAP1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q8N6T3, Q9EPJ9

Gene Symbols

ARFGAP1

Immunogen

Purified recombinant fragment of human ARFGAP1 (AA: 270-414) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunohistochemistry, Western Blot

Clone

1C4E2

Conjugate

Unconjugated

Gene

ARFGAP1

Gene Alias

ADP ribosylation factor GTPase activating protein 1; ADP-ribosylation factor 1 GTPase activating protein; ADP-ribosylation factor 1 GTPase-activating protein; ADP-ribosylation factor GTPase activating protein 1; ADP-ribosylation factor GTPase-activating protein 1; AI115377; ARF GAP 1; Arf GAP1; ARF1 GAP; ARF1-directed GTPase-activating protein; Arf1gap; ARFGAP1; EGK_02194; GAP protein; HRIHFB2281; RP11-261N11.1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

228998, 55738

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2b

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Description

  • ArfGAP1 is a 406 amino acid containing regulatory protein with an Arf-GAP domain known to be involved in the activation of the GTPase activity of ADP ribosylation factor (ARF)
  • ArfGAP1, a GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1), promotes the hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles thus playing an important role in membrane trafficking and/or vesicle transport
  • Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments
  • The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine
  • Two transcript variants encoding different isoforms have been reported
  • Ubiquitous expression of ArfGAP1 is seen in most tissues.