EphB4 Monoclonal Antibody (VEB4-7E4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA549038-Each-of-1 | In Stock | ₹ 65,993.50 |
FERMA549038 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 65,993.50
GST (18%): ₹ 11,878.83
Total Price: ₹ 77,872.33
Antigen
EphB4
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.
P54761
Gene Symbols
EPHB4
Immunogen
The monoclonal antibody VEB4-7E4 recognizes mouse Ephrin type-B receptor 4 (EphB4)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Inhibition Assays, Western Blot
Clone
VEB4-7E4
Conjugate
Unconjugated
Gene
EPHB4
Gene Alias
AI042935; Developmental kinase 2; EPH receptor B4; Ephb4; ephrin receptor EphB4; ephrin type-B receptor 4; Hepatoma transmembrane kinase; HTK; Mdk2; mDK-2; MYK1; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; TYRO11; Tyrosine kinase MYK-1; tyrosine-protein kinase receptor HTK; tyrosine-protein kinase TYRO11
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
13846
Content And Storage
4° C
Isotype
IgG2a
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Description
- The monoclonal antibody VEB4-7E4 marks venous endothelial cells, but not arterial endothelial cells in B16 melanoma cells
- EPHB4 is a receptor tyrosine kinase that belongs to the ephrin receptor family
- Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation
- Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins
- The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands
- Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family
- The protein encoded by EphB4 binds to ephrin-B2 and plays an essential role in vascular development.