FERMA549040

JAM-A (CD321) Monoclonal Antibody (BV16), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549040-Each-of-1 In Stock ₹ 74,048.00

FERMA549040 - Each of 1

₹ 74,048.00

In Stock

Quantity

1

Base Price: ₹ 74,048.00

GST (18%): ₹ 13,328.64

Total Price: ₹ 87,376.64

Antigen

JAM-A (CD321)

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.

Q9Y624

Gene Symbols

F11r

Immunogen

Fusion protein consisting of the extracellular domain of human JAM and the Fc portion of human IgGs

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

BV16

Conjugate

FITC

Gene

F11r

Gene Alias

9130004G24; AA638916; BV11 antigen; CD321; ESTM33; F11 R; F11 receptor; F11 receptor/F11R; F11R; JAM; JAM1; JAM-1; JAMA; JAM-A; Jcam; Jcam1; junction cell adhesion molecule A; junction cell adhesion molecule1; junctional adhesion molecule 1; Junctional adhesion molecule A; KAT; Ly106; PAM-1; Platelet adhesion molecule 1; platelet F11 receptor; UNQ264/PRO301

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

50848

Content And Storage

4° C, store in dark

Isotype

IgG1

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Description

  • CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors
  • CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail
  • The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins
  • CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact
  • CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin
  • CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.