FERMA549116

TLR9 Monoclonal Antibody (5G5), Biotin, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549116-Each-of-1 In Stock ₹ 34,443.00

FERMA549116 - Each of 1

₹ 34,443.00

In Stock

Quantity

1

Base Price: ₹ 34,443.00

GST (18%): ₹ 6,199.74

Total Price: ₹ 40,642.74

Antigen

TLR9

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.

Q9EQU3, Q9NR96

Gene Symbols

Tlr9

Immunogen

Purified fusion protein of extracellular domain of human TLR9 (AA 1-815) and human IgGFc

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

Applications

Inhibition Assays, Western Blot

Clone

5G5

Conjugate

Biotin

Gene

Tlr9

Gene Alias

CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

54106, 81897

Content And Storage

4° C

Isotype

IgG2a

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Description

  • The monoclonal antibody 5G5 reacts with RAW macrophages and TLR9 transfected HEK293 cells, and is cross reactive with canine TLR9
  • The protein encoded by this gene is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity
  • TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
  • They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • The various TLRs exhibit different patterns of expression
  • This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes
  • Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.