MA125840
TOLLIP Monoclonal Antibody (Kimmy-2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA125840-Each-of-1 | In Stock | ₹ 53,311.00 |
MA125840 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,311.00
GST (18%): ₹ 9,595.98
Total Price: ₹ 62,906.98
Antigen
TOLLIP
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q9H0E2, Q9QZ06
Gene Symbols
TOLLIP
Immunogen
Recombinant fragment corresponding to residues 1-274 of mouse Tollip.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
Immunoprecipitation, Western Blot
Clone
Kimmy-2
Conjugate
Unconjugated
Gene
TOLLIP
Gene Alias
4930403G24Rik; 4931428G15Rik; adapter protein; EMBL:AAI33068.1}; FLJ33531; IL-1RAcPIP; toll interacting protein; toll-interacting protein; TOLLIP; tollip {ECO:0000312
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
54472, 54473
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA1-25840 detects TOLLIP from human and mouse samples
- Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila
- These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses
- The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection
- These adaptor molecules include TOLLIP, MyD88, and TRIF
- TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation
- This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.