FERMA549133
TREM1 Monoclonal Antibody (6B1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA549133-Each-of-1 | In Stock | ₹ 39,961.00 |
FERMA549133 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,961.00
GST (18%): ₹ 7,192.98
Total Price: ₹ 47,153.98
Antigen
TREM1
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 0.1% BSA and no preservative
Gene Accession No.
Q9NP99
Gene Symbols
TREM1
Immunogen
Recombinant TREM-1 - IgG1 fusion protein
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot
Clone
6B1
Conjugate
Unconjugated
Gene
TREM1
Gene Alias
CD354; sCD354; soluble CD354; soluble TREM 1; soluble TREM1; sTREM 1; sTREM1; TREM; Trem1; TREM-1; triggering receptor expressed in monocytes 1; triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
54210
Content And Storage
4° C
Isotype
IgG1
Related Products
Description
- The monoclonal antibody 6B1 recognizes both membrane bound and soluble TREM-1
- Also, the monoclonal antibody 6B1 neutralizes the interaction between TREM-1 and its ligand
- TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers
- It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response
- TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.