Complement C5a Monoclonal Antibody (C17/5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | GAU0250502-Each-of-1 | In Stock | ₹ 1,22,731.00 |
GAU0250502 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,22,731.00
GST (18%): ₹ 22,091.58
Total Price: ₹ 1,44,822.58
Antigen
Complement C5a
Classification
Monoclonal
Concentration
1.07 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P01031
Gene Symbols
C5
Immunogen
Purified human C5a.
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgG1 κ
Applications
ELISA, Western Blot
Clone
C17/5
Conjugate
Unconjugated
Gene
C5
Gene Alias
anaphylatoxin; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; C4B1; C4B12; C4B2; C4B3; C4B5; C4F; C5; C5a; C5a anaphylatoxin; C5b; C5D; CH; CO4; complement C5; Complement C5 alpha chain; Complement C5 alpha' chain; Complement C5 beta chain; complement component 5; CPAMD3; CPAMD4; DADB-112B14.11; ECLZB; FLJ17816; FLJ17822; FLJ60561; Hc; He; Hemolytic complement; MGC142298; MGC164979; prepro-C5; RGD1561905
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
727
Content And Storage
4° C, store in dark
Form
Liquid
Related Products
Description
- Specificity: GAU 025-05 reacts with human C5a/C5a (desArg) and cross-reacts with baboon C5a/C5a (desArg)
- Reactivity: For ELISA applications, recombinant C5a coated onto a microtiter well results in a strong reaction
- NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes
- This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge
- An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase
- The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components
- Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections
- Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis.