MA119729

CD263 (TRAIL-R3) Monoclonal Antibody (TRAIL-R3-02), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA119729-Each-of-1 In Stock ₹ 38,092.00

MA119729 - Each of 1

₹ 38,092.00

In Stock

Quantity

1

Base Price: ₹ 38,092.00

GST (18%): ₹ 6,856.56

Total Price: ₹ 44,948.56

Antigen

CD263 (TRAIL-R3)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

O14798

Gene Symbols

TNFRSF10C

Immunogen

TRAIL-R3 (aa 1-280) - hIgGhc fusion protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry

Clone

TRAIL-R3-02

Conjugate

Unconjugated

Gene

TNFRSF10C

Gene Alias

Antagonist decoy receptor for TRAIL/Apo-2L; CD263; cytotoxic TRAIL receptor-3; DCR1; DCR1-TNFR; Decoy receptor 1; decoy TRAIL receptor without death domain; LIT; lymphocyte inhibitor of TRAIL; MGC149501; MGC149502; TNF receptor superfamily member 10c; TNF-related apoptosis-inducing ligand receptor 3; TNFRSF10C; TRAIL receptor 3; TRAIL receptor without an intracellular domain; TRAILR3; TRAIL-R3; TRID; Tumor necrosis factor receptor superfamily member 10C; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain; UNQ321/PRO366

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

8794

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily
  • This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain
  • This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis
  • This gene was found to be a p53-regulated DNA damage-inducible gene
  • The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.