LTBR Monoclonal Antibody (5G11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA549059-Each-of-1 | In Stock | ₹ 72,223.50 |
FERMA549059 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 72,223.50
GST (18%): ₹ 13,000.23
Total Price: ₹ 85,223.73
Antigen
LTBR
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 0.1% BSA and no preservative
Gene Accession No.
P50284
Gene Symbols
Ltbr
Immunogen
Drosophila S2 expressed mouse LTbR Ig fusion protein
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Form
Liquid
Applications
Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot
Clone
5G11
Conjugate
Unconjugated
Gene
Ltbr
Gene Alias
AI256028; CD18; D12S370; LT beta-R; Ltar; LT-beta receptor; LTbetaR; LT-BETA-R; Ltbr; lymphotoxin B receptor; lymphotoxin beta receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); lymphotoxin-beta receptor; TNF receptor-related protein; Tnfbr; TNFCR; TNFR2-RP; TNFR3; TNF-RIII; TNF-R-III; TNFR-III; TNFRrp; TNFR-RP; Tnfrsf3; Tumor necrosis factor C receptor; tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; tumor necrosis factor receptor type III
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
17000
Content And Storage
4° C
Isotype
IgG2a
Related Products
Description
- The monoclonal antibody 5G11 directed against the mouse LTbetaR is able to activate the LTbetaR in an agonistic way and induces NFkappaB activation and secretion of MIP-2 and IL-6 in mouse fibroblast cells
- Therefore, the monoclonal antibody 5G11 can be used to gain more insight into the expression pattern of the LTbetaR and also to investigate molecular mechanisms induced by LTbetaR activation
- The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors
- It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes
- The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta)
- The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells
- Activation of the encoded protein can trigger apoptosis.