TSH Receptor Monoclonal Antibody (49), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA3218-Each-of-1 | In Stock | ₹ 44,811.50 |
MA3218 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
TSH Receptor
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.05% sodium azide
Gene Accession No.
P16473, Q8SPP9
Gene Symbols
TSHR
Immunogen
Purified extracellular domain of recombinant human thyrotropin receptor.
Regulatory Status
RUO
Gene ID (Entrez)
397560, 7253
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunocytochemistry, Western Blot
Clone
49
Conjugate
Unconjugated
Gene
TSHR
Gene Alias
AI481368; CHNG1; hTSHR-I; hypothroid; hyt; LGR3; MGC141920; pet; seven transmembrane helix receptor; thyroid stimulating hormone receptor; thyroid stimulating hormone receptor, isoform 2; thyroid-stimulating hormone receptor; thyroid-stimulating hormone receptor variant; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; TSHR; TSH-R; TSHR; seven transmembrane domain G protein-coupled receptor; TSHRA
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Porcine
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA3-218 detects both glycosylated and nonglycosylated thyroid stimulating hormone receptor (TSHR) from porcine tissues as well as recombinant human TSHR
- MA3-218 has been successfully used in Western blot, immunofluorescence, and ELISA procedures
- By Western blot, this antibody detects a 50 kDa and a 63 kDa protein representing unglycosylated and glycosylated TSHR respectively, in transfected Sf9 cell extract
- By ELISA MA3-218 has been used in TSH competitive inhibition studies
- The MA3-218 antigen is purified extracellular domain of recombinant human thyrotropin receptor
- This antibody recognizes an epitope between amino acid residues 277-296 of human TSHR
- TSH Receptor gene is a membrane protein and a major controller of thyroid cell metabolism
- The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase
- Defects in this gene are a cause of several types of hyperthyroidism
- Three transcript variants encoding different isoforms have been found for this gene.