MA125325

SFPQ Monoclonal Antibody (B92), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA125325-Each-of-1 In Stock ₹ 47,214.50

MA125325 - Each of 1

₹ 47,214.50

In Stock

Quantity

1

Base Price: ₹ 47,214.50

GST (18%): ₹ 8,498.61

Total Price: ₹ 55,713.11

Antigen

SFPQ

Classification

Monoclonal

Concentration

2.1 mg/mL

Formulation

0.01M PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P23246, Q8VIJ6

Gene Symbols

SFPQ

Immunogen

Lysate of mouse bone marrow-derived stromal cell line.

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Radioimmune Assays (RIA), Western Blot

Clone

B92

Conjugate

Unconjugated

Gene

SFPQ

Gene Alias

100 kDa DNA-pairing protein; 1110004P21Rik; 2810416M14Rik; 5730453G22Rik; 9030402K04Rik; AU021830; D4Ertd314e; DNA-binding p52/p100 complex, 100 kDa subunit; Gm12940; hPOMp100; NonO/p54nrb homolog; OTTMUSG00000009329; polypyrimidine tract binding protein associated; polypyrimidine tract-binding protein-associated splicing factor; polypyrimidine tract-binding protein-associated-splicing factor; POMP100; PPP1R140; protein phosphatase 1, regulatory subunit 140; PSF; PTB-associated splicing factor; PTB-associated-splicing factor; REP1; Sfpq; splicing factor proline and glutamine rich; splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated); splicing factor proline/glutamine rich (polypyrimidine tract-binding protein-associated); splicing factor proline/glutamine-rich; splicing factor, proline- and glutamine-rich

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6421, 71514

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recommended positive controls: HeLa
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression
  • SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program
  • Very recently SFPQ was identified as a downstream target of tau, complete nuclear depletion and cytoplasmic accumulation of SFPQ were shown in the neurons and astrocytes of brains with Alzheimer's disease (AD), more strikingly, reduced SFPQ levels may progress together with tau pathology, these observation strongly suggests the important role of SFPQ pathology in neurodegenerative diseases including AD
  • SFPQ protein may appears as 47 kDa, 52 kDa or 100 kDa molecules in various cell types.