MA123240

SAFB Monoclonal Antibody (6F7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA123240-Each-of-1 In Stock ₹ 50,863.50

MA123240 - Each of 1

₹ 50,863.50

In Stock

Quantity

1

Base Price: ₹ 50,863.50

GST (18%): ₹ 9,155.43

Total Price: ₹ 60,018.93

Antigen

SAFB

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

D3YXK2, Q15424

Gene Symbols

SAFB

Immunogen

A synthetic peptide corresponding to amino acids 345-357 (PEARDSKEDGRKF) of the human HET protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

6F7

Conjugate

Unconjugated

Gene

SAFB

Gene Alias

3110021E02Rik; 5330423C17Rik; AU018122; D18386; DKFZp779C1727; E130307D12; glutathione S-transferase fusion protein; HAP; heat-shock protein (HSP27) estrogen response element and TATA box-binding protein; HET; Hsp27 ERE-TATA binding protein; HSP27 ERE-TATA-binding protein; HSP27 estrogen response element-TATA box-binding protein; SAB-B1; Safb; SAF-B; Safb1; SAF-B1; scaffold attachment factor B; scaffold attachment factor B1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

224903, 6294

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Positive control of HeLa, MCF7 cells suggested
  • This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA)
  • This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein
  • Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR
  • The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes
  • It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis
  • This gene is arranged head-to-head with a similar gene whose product has the same functions
  • Multiple transcript variants encoding different isoforms have been found for this gene.