beta-2 Microglobulin Monoclonal Antibody (B2M-01), HRP, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA133436-Each-of-1 | In Stock | ₹ 52,465.50 |
MA133436 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,465.50
GST (18%): ₹ 9,443.79
Total Price: ₹ 61,909.29
Antigen
beta-2 Microglobulin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.01% thimerosal
Gene Accession No.
P61769
Gene Symbols
B2m
Immunogen
Purified human beta-2 Microglobulin
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
ELISA, Western Blot
Clone
B2M-01
Conjugate
HRP
Gene
B2m
Gene Alias
B2m; B2-microglobulin; b2m-W01; b2m-W03; b2m-Z01; b2m-Z02; b2m-Z03; Beta 2 microglobin; Beta 2 microglobulin; beta 2-microglobulin; beta chain of MHC class I molecules; Beta2 microglobulin; beta-2 microglobulin; beta-2 microglobulin preprotein; beta2m; beta2-m; beta-2-microglobin; beta-2-microglobulin; beta-2-microglobulin C-terminal fragment (55 AA); Beta-2-microglobulin form pI 5.3; B-F; CDABP0092; HDCMA22P; IMD43; Lactollin; Ly-m11; MHC Class I; microglobulin beta-2; Orla-B2m
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
567
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- MA1-33436 detects beta 2 Microglobulin from human samples
- This antibody does not cross react with mouse, bovine, canine, rabbit and chicken samples
- Beta-2-microglobulin (B2M) is a 12-14 kDa protein that is a subunit of the major histocompatibility complex (MHC) class I
- Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells, but is absent on erythrocytes
- Beta-2 microglobulin is also found in free form in the plasma
- The amino acid sequence of Beta-2-microglobulin is homologous to the constant regions of immunoglobulin heavy and light chains, with a predominantly beta pleated sheet structure
- The protein is ubiquitously expressed in the cytoplasm, and is involved in antigen processing and presentation
- Beta-2-microglobulin also plays a role in TCR signaling, and downstream signaling in naive CD8+ cells
- Beta 2-microglobulin is encoded by the B2M gene located on chromosome 15
- A mutation in the Beta-2-microglobulin gene has been shown to result in hypercatabolic hypoproteinemia
- Levels of beta 2 microglobulin can be used to assess renal function in kidney transplant recipients
- Beta-2-microglobulin that protein can be used as a prognostic marker for HIV infection.