beta Tubulin Loading Control, Biotin, clone: BT7R, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA516308BTI-Each-of-1 | In Stock | ₹ 27,990.50 |
MA516308BTI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,990.50
GST (18%): ₹ 5,038.29
Total Price: ₹ 33,028.79
Antigen
Beta-Tubulin Loading Control
Classification
Monoclonal
Concentration
1mg/mL
Gene
TUBB
Gene Alias
beta 5-tubulin, beta Ib tubulin, beta-4 tubulin, tubulin beta chain, tubulin beta polypeptide, tubulin beta-1 chain, tubulin beta-5 chain, tubulin, beta polypeptide
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
100347858, 100358689, 203068, 396254, 396427, 545486, 679312, 81027
Content And Storage
Store at 4°C. Do not freeze.
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
BT7R
Conjugate
Biotin
Gene Accession No.
P07437, Q9H4B7, A2AQ07
Gene Symbols
TUBB, TUBB1
Immunogen
KLH conjugated peptide of the N-terminus of Beta-Tubulin.
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Chicken, Human, Mouse, Non-human Primate, Rabbit, Rat
Product Type
Antibody
Isotype
IgG2a
Related Products
Description
- MA5-16308-BTIN has successfully been used for Western blot, IHC (P), FACS, ELISA and ICC/IF Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules
- Beta-III tubulin is primarily expressed in neurons and may be involved in neurogenesis, axon guidance and maintece
- Mutations in the beta tubulin gene are the cause of congenital fibrosis of the extraocular muscles type 3
- Beta-III tubulin was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues
- Glutamate residues at the C-terminus of beta III tubulin can be glutamylated
- The precise function of such modifications is unclear
- Tubulin is phosphorylated on Ser-172 by CDK1 during cell cycle progression
- Ser-172 phosphorylation inhibits tubulin incorporation into microtubules
- Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55 kDa subunits: alpha and Beta
- Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton
- Because beta-tubulin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting.