Factor VII Monoclonal Antibody (5031), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA143011-Each-of-1 | In Stock | ₹ 41,385.00 |
MA143011 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
Factor VII
Classification
Monoclonal
Concentration
14.1 mg/mL
Formulation
50% water with 50% glycerol and no preservative
Gene Accession No.
P08709
Gene Symbols
F7
Immunogen
Human factor VII/VIIa.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Radioimmune Assays (RIA), Western Blot
Clone
5031
Conjugate
Unconjugated
Gene
F7
Gene Alias
AI132620; Cf7; Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; F7; Factor 7; Factor VII heavy chain; Factor VII light chain; Factor7; FVII; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA
Host Species
Mouse
Purification Method
Ammonium sulfate precipitation, Ion-exchange chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2155
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-43011 detects Factor VII in human samples
- MA1-43011 has successfully been used in radioimmunassays, western blot and ELISA applications
- MA1-43011 was derived from human factor VII, factor VIIa and BFPRck factor VIIa
- Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis
- This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis
- Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond
- In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa
- Defects in F7 production can cause coagulopathy.