Factor X/Xa Monoclonal Antibody (5050), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA143013-Each-of-1 | In Stock | ₹ 41,385.00 |
MA143013 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
Factor X/Xa
Classification
Monoclonal
Concentration
7.6 mg/mL
Formulation
50% water with 50% glycerol and no preservative
Gene Accession No.
P00742
Gene Symbols
F10
Immunogen
Purified human Factor X
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Affinity Purification, ELISA, Inhibition Assays, Radioimmune Assays (RIA), Western Blot
Clone
5050
Conjugate
Unconjugated
Gene
F10
Gene Alias
Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
2159
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This antibody detects the heavy chains of human factor Xa and X; does not bind bovine factor X or BEGRck-Xa
- Does not recognize murine or porcine X via Western blot
- Inhibitory properties: inhibits PT, prothrombinase and partially APTT, but not amidase activity
- Purity >95% by SDS-PAGE
- Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR
- Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases
- The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway)
- The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting
- Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.