MA143021
Factor XI Monoclonal Antibody (5061), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA143021-Each-of-1 | In Stock | ₹ 41,385.00 |
MA143021 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
Factor XI
Classification
Monoclonal
Concentration
10.8 mg/mL
Formulation
50% water with 50% glycerol and no preservative
Gene Accession No.
P03951
Gene Symbols
F11
Immunogen
Human factor XI.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Radioimmune Assays (RIA), Western Blot
Clone
5061
Conjugate
Unconjugated
Gene
F11
Gene Alias
1600027G01Rik; AI503996; Cf11; Coagulation factor XI; Coagulation factor XIa heavy chain; Coagulation factor XIa light chain; F11; FXI; LRRGT00086; plasma thromboplastin antecedent; PTA
Host Species
Mouse
Purification Method
Ammonium sulfate precipitation, Ion-exchange chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2160
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-43021 detects Factor XI in human samples
- MA1-43021 has successfully been used in western blot (non-reducing) and radioimmunoassays applications
- MA1-43021 was derived from human factor XI
- This gene encodes coagulation factor XI of the blood coagulation cascade
- This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds
- During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds
- This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX
- Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.