MA1813

CRALBP Monoclonal Antibody (B2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA1813-Each-of-1 In Stock ₹ 49,973.50

MA1813 - Each of 1

₹ 49,973.50

In Stock

Quantity

1

Base Price: ₹ 49,973.50

GST (18%): ₹ 8,995.23

Total Price: ₹ 58,968.73

Antigen

CRALBP

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P10123, P12271, Q9Z275

Gene Symbols

RLBP1

Immunogen

Human recombinant CRALBP.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone

B2

Conjugate

Unconjugated

Gene

RLBP1

Gene Alias

3110056M11Rik; cellular retinaldehyde-binding protein; cellular retinaldehyde-binding protein-1; CRALBP; retinaldehyde binding protein 1; retinaldehyde-binding protein 1; retinaldehyde-binding protein precursor; Rlbp1

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

19771, 282038, 293049, 6017

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA1-813 detects CRALBP protein in bovine, human, mouse, non-human primate and rat samples
  • MA1-813 has successfully been used in Western blot, immunohistochemistry, immunoprecipitation, and immunofluorescence procedures
  • By Western blot, this antibody detects a 37 kDa protein representing human recombinant CRALBP
  • The MA1-813 immunogen is purified human recombinant CRALBP
  • Cellular retinaldehyde-binding protein (CRALBP) plays an important role in the regeneration of 11-cis-retinal for use in rod visual pigments such as opsin and rhodopsin
  • Once 11-cis-retinal is photoisomerized in the rod outer segment, it is converted to all-trans-retinal and further modified into all-trans-retinol
  • All-trans-retinol then diffuses into the retinal pigment epithelium (RPE) to be converted back to 11-cis-retinol and further oxidized into 11-cis-retinal (both by CRALBP)
  • Genetic mutations involving CRALBP's lack of function have been linked to visual disease such as bothnia dystrophy, retinitis punctata albescens, retina pigmentosa, and Newfoundland rod-cone dystrophy
  • The presence of CRALBP serves as a marker for RPE and Muller glial cells of the retina.