PA1080

RANBP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1080-Each-of-1 In Stock ₹ 47,837.50

PA1080 - Each of 1

₹ 47,837.50

In Stock

Quantity

1

Base Price: ₹ 47,837.50

GST (18%): ₹ 8,610.75

Total Price: ₹ 56,448.25

Antigen

RANBP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RANBP1

Gene Alias

HpaII tiny fragments locus 9A; hpaII tiny fragments locus 9a protein; Htf9a; Htf9-a; Htf9-a/RanBP1; RAN binding protein 1; ran-binding protein 1; RANBP1; RANG; Ran-specific GTPase-activating protein; testis secretory sperm-binding protein Li 221n

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19385, 5902

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P34022, P43487

Gene Symbols

RANBP1

Immunogen

Synthetic peptide corresponding to residues M(1) A A A K D T H E D H D T S T E N T(18) C of human RanBP1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-080 detects Ran binding protein 1 (RanBP1) from human and mouse cells
  • PA1-080 has been successfully used in Western blot procedures
  • By Western blot, this antibody detects an ∽30 kDa protein representing RanBP1 from HeLa cell extract
  • The PA1-080 immunogen is a synthetic peptide corresponding to residues M(1) A A A K D T H E D H D T S T E N T(18) C of human RanBP1
  • The PA1-080 immunizing peptide (Cat
  • # PEP-128) is available for use in neutralization and control experiments
  • Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN
  • RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP
  • RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1)
  • The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog
  • In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.