Protein APC Monoclonal Antibody (FE9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA191039-Each-of-1 | In Stock | ₹ 50,507.50 |
MA191039 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,507.50
GST (18%): ₹ 9,091.35
Total Price: ₹ 59,598.85
Antigen
Protein APC
Classification
Monoclonal
Concentration
0.1 mg/mL
Formulation
0.05M sodium phosphate with 0.2% gelatin and 0.1% sodium azide; pH 7.5
Gene Accession No.
P25054, P70478, Q61315
Gene Symbols
Apc
Immunogen
synthetic peptide corresponding to the N-terminal 35 amino acid residues of APC.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
FE9
Conjugate
Unconjugated
Gene
Apc
Gene Alias
adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; adenomatous polyposis coli protein; AI047805; APC; APC, WNT signaling pathway regulator; AU020952; AW124434; BTPS2; CC1; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FAP; FPC; GS; mAPC; Min; multiple intestinal neoplasia; PPP1R46; Protein APC; protein phosphatase 1, regulatory subunit 46; RATAPC; truncated adenomatosis polyposis coli; WNT signaling pathway regulator
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
11789, 24205, 324
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- Reacts with all full length and truncated APC proteins
- MA1-91039 has been successfully used in Western blot applications, where a band of approximately 312 kDa is predicted to be detected
- Suggested positive controls for this product are HCT116 cells for p300 and SW480 cells for truncated APC (p147)
- This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway
- It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis
- Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy
- Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.