PA128838

GLI2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA128838-Each-of-1 In Stock ₹ 49,350.50

PA128838 - Each of 1

₹ 49,350.50

In Stock

Quantity

1

Base Price: ₹ 49,350.50

GST (18%): ₹ 8,883.09

Total Price: ₹ 58,233.59

Antigen

GLI2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GLI2

Gene Alias

AW546128; CJS; GLI family zinc finger 2; GLI family zinc finger protein 2; GLI2; GLI-Kruppel family member GLI2; glioma-associated oncogene family zinc finger 2; HPE9; oncogene GLI2; PHS2; Tax helper protein; tax helper protein 1; tax helper protein 2; tax-responsive element-2 holding protein; tax-responsive element-25-bp sequence binding protein; Thp; THP1; THP2; zinc finger protein GLI2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14633, 2736

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration

1.02 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

P10070, Q0VGT2

Gene Symbols

GLI2

Immunogen

synthetic peptide LRGAPSASRGSYTQQPR-C conjugated to KLH, corresponding to amino acids 1193-1209 of Mouse Gli2

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Description PA1-28838 detects Gli2 from mouse samples
  • Gli-2 belongs to the C2H2-type zinc finger protein subclass of the Gli family
  • Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs
  • These motifs contain conserved H-C links
  • Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell
  • The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression
  • It is also thought to play a role during embryogenesis
  • The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.