UCP3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA124895-Each-of-1 | In Stock | ₹ 52,332.00 |
PA124895 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,332.00
GST (18%): ₹ 9,419.76
Total Price: ₹ 61,751.76
Antigen
UCP3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ucp3
Gene Alias
AI645527; mitochondrial uncoupling protein 3; Slc25a9; solute carrier family 25 member 9; UCP 3; UCP3; UCP-3; uncoupling protein; uncoupling protein 3; uncoupling protein 3 (mitochondrial, proton carrier); uncoupling protein 3, mitochondrial
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22229, 25708, 7352
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1.1 mg/mL
Formulation
0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.
P55916, P56499, P56501
Gene Symbols
Ucp3
Immunogen
Synthetic peptide, conjugated to KLH, corresponding to residues 254-267 of human UCP3 with an N-terminal added lysine.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: human and mouse skeletal muscle, mitochondrial extract of rat brown adipose tissue
- The corresponding sequence in rat and mouse UCP3 differ by 4 and 3 amino acids respectively
- This antibody exhibits no cross reactivity with UCP1 or UCP2
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- The uncoupling protein UCP1 (formerly designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria
- UCP1 forms a dimer that acts as a proton channel, which can uncouple oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane
- This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism
- UCP2 is a structurally related protein that also uncouples mitochondrial respiration
- It is more widely expressed in human and mouse tissues, including white adipose tissue and muscle, than is UCP1
- UCP2 is thought to play a role in body weight regulation
- An additional UCP family member, UCP3, is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.