Phospho-Btk (Ser180) Monoclonal Antibody (3i5 (3D3)), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA191571-Each-of-1 | In Stock | ₹ 50,240.50 |
MA191571 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,240.50
GST (18%): ₹ 9,043.29
Total Price: ₹ 59,283.79
Antigen
Phospho-Btk (Ser180)
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites diluted in 0.01M HEPES buffered saline with 0.1mg/mL BSA, 150mM NaCl, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
Q06187
Gene Symbols
BTK
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding Ser180 of human Btk
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Western Blot
Clone
3i5 (3D3)
Conjugate
Unconjugated
Gene
BTK
Gene Alias
agammaglobulinaemia tyrosine kinase; agammaglobulinemia tyrosine kinase; AGMX1; AI528679; AT; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton's tyrosine kinase; BTK; dominant-negative kinase-deficient Brutons tyrosine kinase; IMD1; Kinase EMB; MGC126261; MGC126262; OTTHUMP00000023677; PSCTK1; RP1-164F3.2; truncated Bruton agammaglobulinemia tyrosine kinase; tyrosine-protein kinase BTK; Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB); tyrosine-protein kinase BTK isoform (lacking exon 13 to 17); tyrosine-protein kinase BTK isoform (lacking exon 14); xid; XLA; X-linked immune deficiency
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
695
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases
- Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders
- It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9
- The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens
- BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipopolysaccharide signal transduction.