CDK7 Monoclonal Antibody (31TF2-1F8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA3001-Each-of-1 | In Stock | ₹ 47,748.50 |
MA3001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,748.50
GST (18%): ₹ 8,594.73
Total Price: ₹ 56,343.23
Antigen
CDK7
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.05% sodium azide
Gene Accession No.
P50613, Q03147
Gene Symbols
CDK7
Immunogen
Synthetic peptide MALDVKSRAKRYEKLDFLGEGQ corresponding to aa 1-22 of human CDK7
Regulatory Status
RUO
Gene ID (Entrez)
1022, 12572
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Clone
31TF2-1F8
Conjugate
Unconjugated
Gene
CDK7
Gene Alias
39 KDa protein kinase; 39 protein kinase; AI323415; AI528512; C230069N13; CAK; CAK1; CDK; CDK7; CDK-activating kinase; CDK-activating kinase 1; Cdkn7; cell division protein kinase 7; CR4 protein kinase; CRK4; CRK4 PK (CDC2-related-kinase-4 protein kinase); cyclin dependent kinase 7; cyclin-dependent kinase 7; cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase); EC 2.7.11.22; EC 2.7.11.23; HCAK; homolog of Xenopus MO15 Cdk-activating kinase; kinase subunit of CAK; MO15; Mpk-7; OTTHUMP00000222032; OTTHUMP00000222033; p39 Mo15; p39MO15; Protein-tyrosine kinase MPK-7; serine/threonine kinase stk1; serine/threonine protein kinase 1; serine/threonine protein kinase MO15; Serine/threonine-protein kinase 1; STK1; TFIIH basal transcription factor complex kinase subunit
Host Species
Mouse
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- MA3-001 has been used successfully in Western blotting to detect Cyclin dependent kinase 7 in human lysates
- The trimeric complex of CDK7, cyclin H and MNAT1, functions as a Cdk-activating kinase (CAK)
- It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair
- This complex is thought to serve as a direct link between the regulation of transcription and the cell cycle
- The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1)
- CDK7 may be a target of germline cancer-inducing mutations.