Active/Pro-Caspase 3 Monoclonal Antibody (31A1067), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA191637-Each-of-1 | In Stock | ₹ 53,133.00 |
MA191637 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,133.00
GST (18%): ₹ 9,563.94
Total Price: ₹ 62,696.94
Antigen
Active/Pro-Caspase 3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P42574, P55213, P70677, Q95ND5
Gene Symbols
CASP3
Immunogen
Full-length recombinant human caspase-3 protein was used as immunogen. The antibody recognizes an epitope in the large domain subunit of Caspase-3. As such it will recognize pro Caspase-3 and the large subunit cleavage fragment.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Hamster, Human, Mouse, Porcine, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunomicroscopy, Western Blot
Clone
31A1067
Conjugate
Unconjugated
Gene
CASP3
Gene Alias
A830040C14Rik; AC-3; Apopain; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; IRP; Lice; mLdy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
100689061, 12367, 25402, 397244, 836
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Predicted molecular weight: 31kDa
- Positive Control: Staurosporine-treated HeLa or Jurkat cell lysate
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family
- Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis
- Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme
- This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10
- It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease
- Alternative splicing of this gene results in two transcript variants that encode the same protein.