Mu-Calpain Monoclonal Antibody (9A4H8D3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA3940-Each-of-1 | In Stock | ₹ 49,706.50 |
MA3940 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,706.50
GST (18%): ₹ 8,947.17
Total Price: ₹ 58,653.67
Antigen
Mu-Calpain
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
O35350, P06815, P07384, P35750, P97571, Q27970
Gene Symbols
CAPN1
Immunogen
Purified bovine skeletal muscle 80 kDa mu-calpain subunit.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Bovine, Hamster, Human, Mouse, Porcine, Rabbit, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone
9A4H8D3
Conjugate
Unconjugated
Gene
CAPN1
Gene Alias
calcium activated neutral protease; calcium-activated neutral protease 1; calcium-activated neutral proteinase 1; calcium-dependent protease; calpain; calpain 1; calpain 1 large subunit; calpain 1, (mu/I) large subunit; calpain 1, large subunit; calpain mu-type; calpain, large polypeptide L1; calpain-1 catalytic subunit; Calpain-1 large subunit; Calpain-I; Calpain-II; CANP; CANP 1; Canp1; CANPL1; Capa1; Capa-1; Capn1; Cell proliferation-inducing gene 30 protein; cell proliferation-inducing protein 30; Cls1; I79_024883; micromolar calcium-activated neutral protease 1; micromolar calcium-activated neutral protease 1 isoform A; micromolar calcium-activated neutral protease 1 isoform B; micromolar calcium-dependent neutral protease large subunit; micromolar-calpain; mucalpain; mu-calpain; mu-calpin; muCANP; muCL; PIG30; SPG76
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
100009089, 100758636, 12333, 281661, 29153, 397027, 823
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA3-940 detects mu-calpain from human platelets and erythrocytes, bovine platelets, heart and skeletal muscle, rat myoblasts, kidney, liver and spleen, mouse lung, pig cultured cells and hamster and rabbit samples
- This antibody does not cross-react with m-calpain, n-calpain, calmodulin or calpastatin
- MA3-940 has been successfully used in Western blot, immunofluorescence, immunohistochemistry, and immunocytochemistry procedures
- By Western blot, this antibody detects an 80 kDa protein representing mu-calpain from human platelets and erythrocytes and HeLa and A431 cell lysates
- Immunocytochemical staining of mu-calpain in LLC-PK1 cells with MA3-940 results in diffuse cytoplasmic staining
- This product has not been shown to be effective in immunoprecipitation experiments
- The MA3-940 antigen is purified bovine skeletal muscle 80 kDa mu-calpain subunit
- This antibody recognizes an epitope between amino acids 465-520 (domain III) of human mu-calpain
- The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases
- The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins
- The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit
- This gene encodes the large subunit of the ubiquitous enzyme, calpain 1
- Several transcript variants encoding two different isoforms have been found for this gene
- Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.