Caspase 3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA129157-Each-of-1 | In Stock | ₹ 52,154.00 |
PA129157 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,154.00
GST (18%): ₹ 9,387.72
Total Price: ₹ 61,541.72
Antigen
Caspase 3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CASP3
Gene Alias
A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mLdy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
100008840, 12367, 25402, 836
Content And Storage
4° C, do not freeze
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
10mM PBS with 0.2% BSA and 0.1% sodium azide
Gene Accession No.
P42574, P55213, P70677, Q8MJC3
Gene Symbols
CASP3
Immunogen
Recombinant full length human caspase 3 protein.
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rabbit, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Possible positive controls are Jurkat cells, and tonsil
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family
- Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis
- Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme
- This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10
- It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease
- Alternative splicing of this gene results in two transcript variants that encode the same protein.