MABN838MI
MilliporeSigma™ anti-Retinal Dehydrogenase 1/ALDH1A1 Clone: 8D7.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN838MI-Each-of-1 | In Stock | ₹ 46,799.76 |
MABN838MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,799.76
GST (18%): ₹ 8,423.957
Total Price: ₹ 55,223.717
Antigen
Retinal Dehydrogenase 1/ALDH1A1
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P00352
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
8D7.1
Formulation
Purified mouse monoclonal IgG1k antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
ALDH1A1, ALDC, ALDH1, PUMB1
Immunogen
GST-tagged recombinant protein corresponding to the N-terminal of human Retinal Dehydrogenase 1/ALDH1A1.
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_000680
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG1 κ
Related Products
Description
- Specifically detects Retinal Dehydrogenase 1/ALDH1A1 Clone: 8D7.1 in Human samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting Retinal dehydrogenase 1 (EC 1.2.1.36; UniProt P00352; also known as Aldehyde dehydrogenase cytosolic, Aldehyde dehydrogenase family 1 member A1, ALDH-E1, ALHDII, RALDH 1, RalDH1) is encoded by the ALDH1A1 (also known as ALDC, ALDH1, PUMB1) gene (Gene ID 216) in human
- ALDH1A1, ALDH1A2, and ALDH1A3 constitute the ALDH1A subfamily of aldehyde dehydrogenases that catalyze the oxidation of all-trans retinal and 9-cis retinal to all-trans retinoic acid and 9-cis retinoic acid, respectively
- In addition to its role in detoxifing 4-hydroxy-2-nonenal (4-HNE) in the lens and cornea, ALDH1A1 is also involved in many other biological processes, including stem cell maintenance, UV-radiation resistance, melanogenesis, and spermatogenesis, by catalyzing the conversion of specific aldehydes to their corresponding carboxylic acids.