MilliporeSigma™ Mouse anti-Anoctamin-5, Clone: 5F7,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS501MI-Each-of-1 | In Stock | ₹ 38,958.86 |
MABS501MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,958.86
GST (18%): ₹ 7,012.595
Total Price: ₹ 45,971.455
Antigen
Anoctamin-5
Classification
Monoclonal
Formulation
Mouse monoclonal IgMκ in buffer containing supernatant without preservatives.
Gene Symbols
ANO5; GDD1; TMEM16E
Immunogen
Linear peptide corresponding to mouse Anoctamin-5 near the C-terminus.
Quantity
200 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_998764
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications
Western Blot
Clone
5F7
Gene Accession No.
Q75V66
Host Species
Mouse
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse
Isotype
IgM κ
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Description
- Specifically detects Anoctamin-5 clone: 5F7 in Human, Mouse samples, and it is validated for Western Blotting Anoctamin-5 (UniProt Q75V66; also known as Gnathodiaphyseal dysplasia 1 protein, Integral membrane protein GDD1, Transmembrane protein 16E) is encoded by the ANO5 (also known as GDD1, LGMD2L, TMEM16E) gene (Gene ID 203859) in human
- The human Anoctamins (ANO) compose a family of at least ten proteins, all exhibiting eight transmembrane domains and a DUF590 domain of unknown function
- The ANO1, ANO2, ANO6, ANO8, and ANO9 are characterized to code for the elusive calcium-activated chloride channels (CaCCs)
- While the physiological function of anoctamin-5 is not yet characterized, dominant mutations in ANO5 have been found in the rare skeletal disorder gnathodiaphyseal dysplasia
- In addition, recessive mutations in ANO5 are found to cause proximal muscular dystrophy (LGMD2L) and distal Miyoshi myopathy (MMD3).