NBP229432

NKX2.2 Antibody (NX2/294), Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP229432-Each-of-1 In Stock ₹ 46,814.00

NBP229432 - Each of 1

₹ 46,814.00

In Stock

Quantity

1

Base Price: ₹ 46,814.00

GST (18%): ₹ 8,426.52

Total Price: ₹ 55,240.52

Antigen

NKX2.2

Classification

Monoclonal

Concentration

0.2 mg/mL

Dilution

Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml

Gene Alias

Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Gene ID (Entrez)

4821

Target Species

Human, Mouse, Rat, Chicken

Form

Purified

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

NX2/294

Conjugate

Unconjugated

Gene Accession No.

O95096

Gene Symbols

NKX2-2

Immunogen

Human full-length recombinant NKX2.2 protein (Uniprot: O95096)

Quantity

0.1 mg

Primary or Secondary

Primary

Test Specificity

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Content And Storage

Store at 4C.

Isotype

IgG2b κ

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Description

  • NKX2.2 Monoclonal specifically detects NKX2.2 in Human, Mouse, Rat, Chicken samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.