NBP229440

EGFR Antibody (GFR450), Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP229440-Each-of-1 In Stock ₹ 47,704.00

NBP229440 - Each of 1

₹ 47,704.00

In Stock

Quantity

1

Base Price: ₹ 47,704.00

GST (18%): ₹ 8,586.72

Total Price: ₹ 56,290.72

Antigen

EGFR

Classification

Monoclonal

Concentration

0.2 mg/ml

Dilution

Flow Cytometry 0.5-1 μg/million cells in 0.1 mL, Immunohistochemistry, Immunohistochemistry-Paraffin 0.5-1.0 μg/mL, Protein Array, Immunofluorescence 1-2 μg/mL

Gene Alias

avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Content And Storage

Store at 4C.

Isotype

IgG2a κ

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array, Immunofluorescence

Clone

GFR450

Conjugate

Unconjugated

Gene Accession No.

P00533

Gene Symbols

EGFR

Immunogen

Recombinant extracellular domain of human EGFR protein (Uniprot: P00533)

Quantity

0.1 mg

Research Discipline

Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases

Gene ID (Entrez)

1956

Target Species

Human, Mouse (Negative)

Form

Purified

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Description

  • EGFR Monoclonal specifically detects EGFR in Human, Mouse (Negative) samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array, Immunofluorescence.