NMDAR2C Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | OPA104020-Each-of-1 | In Stock | ₹ 48,905.50 |
OPA104020 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
NMDAR2C
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GRIN2C
Gene Alias
GluN2C; GluRepsilon3; glutamate [NMDA] receptor subunit epsilon-3; glutamate ionotropic receptor NMDA type subunit 2C; glutamate receptor; glutamate receptor ionotropic, NMDA 2C; glutamate receptor ionotropic, NMDA 2C; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2C; glutamate receptor, ionotropic, NMDA2C; glutamate receptor, ionotropic, NMDA2C (epsilon 3); glutamate receptor, ionotropic, N-methyl D-aspartate 2C; Grin2c; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2C; NMDA glutamate receptor; NMDAR2C; N-methyl D-aspartate receptor subtype 2C; N-methyl-D-aspartate receptor subunit 2C; NR2; NR2C
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14813, 24411, 2905
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Immunoprecipitation, Western Blot
Concentration
0.2 mg/mL
Formulation
antibody with no preservative; pH 7.4
Gene Accession No.
Q00961, Q01098, Q14957
Gene Symbols
GRIN2C
Immunogen
Fusion protein from the N-terminal region of the NR2C subunit of rat GRIN2C
Quantity
10 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody detects predominantly the NR2C isoform but may show low level cross-reactivity with the NR2A and NR2B isoforms
- In Western blot, this antibody detects a ∽140 kDa protein representing NR2C in rat brain homogenate
- Faint bands representing the NR2A and NR2B isoforms at 180 KDa may also be observed
- Immunohistochemical staining in rat brain with OPA1-04020 yields a pattern consistent with plasma membrane staining
- Reconstitute with 50 μL of PBS
- The NMDA Receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimers, epilepsy and ischemic neuronal cell death
- The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS
- The NMDAR is also potentiated by protein phosphorylation
- The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ
- Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of th NMDAR2 (NR2 A-D) subunits.