PA11051

Perilipin 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA11051-Each-of-1 In Stock ₹ 50,107.00

PA11051 - Each of 1

₹ 50,107.00

In Stock

Quantity

1

Base Price: ₹ 50,107.00

GST (18%): ₹ 9,019.26

Total Price: ₹ 59,126.26

Antigen

Perilipin 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Plin1

Gene Alias

6030432J05Rik; adipocyte lipid droplet binding protein; FPLD4; Lipid droplet-associated protein; PERI; PERIA; perilipin; perilipin 1; perilipin A; perilipin B; perilipin-1; PLIN; PLIN1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

103968, 25629

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P43884, Q8CGN5

Gene Symbols

Plin1

Immunogen

Synthetic peptide corresponding to the residues C E(502) P I L G R T Q Y S Q L R K K S(517) of rat Perilipin A.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-1051 detects perilipin A from rat and 3T3-L1 cell extract
  • PA1-1051 has been successfully used in Western blot procedures
  • By Western blot, this antibody detects an ∽62 kDa protein representing perilipin A from 3T3-L1 cell extract The PA1-1051 immunogen is a synthetic peptide corresponding to the residues C E(502) P I L G R T Q Y S Q L R K K S(517) of rat Perilipin A
  • This sequence is 93% conserved in humans
  • The PA1-1051 immunizing peptide (Cat
  • # PEP-169) is available for use in neutralization and control experiments
  • Adipose tissue is an energy reserve in animals and is strictly regulated in nondomestic species
  • Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), resistin, and perilipin
  • Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated
  • This protein is localized exclusively to the surface of lipid droplets
  • In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A
  • Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body
  • Perilipin expression is limited to adipocytes and steroidogenic cells
  • There are currently two known isoforms, Perilipin A and B
  • Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.