PA11043

Synaptophysin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA11043-Each-of-1 In Stock ₹ 50,107.00

PA11043 - Each of 1

₹ 50,107.00

In Stock

Quantity

1

Base Price: ₹ 50,107.00

GST (18%): ₹ 9,019.26

Total Price: ₹ 59,126.26

Antigen

Synaptophysin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Syp

Gene Alias

A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

101112034, 20977, 24804, 280937, 6855

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P07825, P08247, P20488, Q62277

Gene Symbols

Syp

Immunogen

Synthetic peptide corresponding to residues G(253) P G G Y G P Q D S Y G P Q G G Y Q P D(272) of rat Synaptophysin.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Human, Mouse, Ovine, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-1043 detects Synaptophysin in rat, mouse, bovine, and sheep samples
  • PA1-1043 has been successfully used in Western blot and immunofluorescence procedures
  • By Western blot, this antibody detects a ∽33.8 kDa protein representing Synaptophysin in rat, mouse and bovine brain tissue as well as sheep retinas
  • The PA1-1043 immunogen is a synthetic peptide corresponding to residues G(253) P G G Y G P Q D S Y G P Q G G Y Q P D(272) of rat Synaptophysin
  • This sequence is conserved in many species including human, mouse and bovine
  • The PA1-1043 immunizing peptide (Cat
  • # PEP-279) is available for use in neutralization and control experiments
  • Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons
  • Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis
  • It is also involved in the regulation of short-term and long-term synaptic plasticity
  • Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors
  • Mutations in the gene can result in mental retardation, X-linked 96.