PA14132

RAD17 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA14132-Each-of-1 In Stock ₹ 46,502.50

PA14132 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

RAD17

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Rad17

Gene Alias

CCYC; cell cycle checkpoint protein (RAD17); cell cycle checkpoint protein RAD17; DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; hRad17; MmRad24; R24L; RAD1 homolog; RAD17; RAD17 (Ser647); RAD17 checkpoint clamp loader component; RAD17 homolog; RAD17 homolog (S. pombe); Rad17 like protein; Rad17-like protein; Rad17p; RAD17SP; RAD24; RF-C activator 1 homolog; RF-C/activator 1 homolog; YOR368W

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5884

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O75943

Gene Symbols

Rad17

Immunogen

Synthetic peptide corresponding to residues N(2) Q V T D W V D P S F D D F(15) of human RAD17.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-4132 detects human RAD17
  • PA1-4132 has been successfully used in Western blot procedures
  • By Western blot this antibody detects a ∽66 kDa protein representing RAD17 in human heart lysate
  • The PA1-4132 immunogen is a synthetic peptide corresponding to residues N(2) Q V T D W V D P S F D D F(15) of human RAD17
  • Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage
  • It has a weak ATPase activity required for binding to chromatin
  • Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation
  • May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.