PA143048

Factor XI Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA143048-Each-of-1 In Stock ₹ 25,943.50

PA143048 - Each of 1

₹ 25,943.50

In Stock

Quantity

1

Base Price: ₹ 25,943.50

GST (18%): ₹ 4,669.83

Total Price: ₹ 30,613.33

Antigen

Factor XI

Classification

Polyclonal

Conjugate

Unconjugated

Gene

F11

Gene Alias

1600027G01Rik; AI503996; Cf11; Coagulation factor XI; Coagulation factor XIa heavy chain; Coagulation factor XIa light chain; F11; FXI; LRRGT00086; plasma thromboplastin antecedent; PTA

Host Species

Sheep

Purification Method

Ammonium sulfate precipitation, Ion-exchange chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2160

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Western Blot

Concentration

12.4 mg/mL

Formulation

50% water with 50% glycerol and no preservative

Gene Accession No.

P03951

Gene Symbols

F11

Immunogen

Human Factor XI.

Quantity

1 mg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-43048 detects Factor XI in human samples
  • PA1-43048 has successfully been used in Western blot and ELISA applications
  • PA1-43048 was derived from human factor XI
  • This gene encodes coagulation factor XI of the blood coagulation cascade
  • This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds
  • During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds
  • This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX
  • Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.