Factor XIII Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA143050-Each-of-1 | In Stock | ₹ 25,943.50 |
PA143050 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,943.50
GST (18%): ₹ 4,669.83
Total Price: ₹ 30,613.33
Antigen
Factor XIII
Classification
Polyclonal
Formulation
50% water with 50% glycerol and no preservative
Gene Accession No.
P00488
Gene Symbols
F13A1
Immunogen
Human Factor XIII.
Quantity
1 mg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Gene
F13A1
Gene Alias
bA525O21.1 (coagulation factor XIII, A1 polypeptide); coagulation factor XIII; coagulation factor XIII A chain; Coagulation factor XIII B chain; coagulation factor XIII, A polypeptide; coagulation factor XIII, A1 polypeptide; coagulation factor XIII, B polypeptide; coagulation factor XIIIa; F13; F13A; F13A1; F13B; Factor 13; factor viiia; factor XIIIa; Factor13; fibrin stabilizing factor, A subunit; fibrinoligase; fibrin-stabilizing factor B subunit; FSF, A subunit; FXIIIB; Protein-glutamine gamma-glutamyltransferase A chain; protein-glutamine gamma-glutamyltransferase B chain; TGase; transglutaminase A chain; Transglutaminase B chain; transglutaminase. plasma
Host Species
Sheep
Purification Method
Ammonium sulfate precipitation, Ion-exchange chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2162
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- PA1-43050 detects Factor XIII in human samples
- PA1-43050 has successfully been used in Western blot and ELISA applications
- PA1-43050 was derived from human factor XIII
- This gene encodes the coagulation factor XIII A subunit
- Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade
- Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits
- The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules
- Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin
- Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII
- This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot
- It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin
- Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone
- These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.