PA14316

CIDEC Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA14316-Each-of-1 In Stock ₹ 49,706.50

PA14316 - Each of 1

₹ 49,706.50

In Stock

Quantity

1

Base Price: ₹ 49,706.50

GST (18%): ₹ 8,947.17

Total Price: ₹ 58,653.67

Antigen

CIDEC

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CIDEC

Gene Alias

cell death activator CIDE-3; cell death inducing DFFA like effector c; cell death-inducing DFFA-like effector c; cell death-inducing DFFA-like effector protein C; CID; cide 3; CIDE3; CIDE-3; CIDE-3alpha; Cidec; fat specific gene 27; fat specific protein 27; fat-specific protein FSP27; Fat-specific protein FSP27 homolog; FPLD5; FSP27

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14311, 63924

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P56198, Q96AQ7

Gene Symbols

CIDEC

Immunogen

Synthetic peptide corresponding to residues L(10) L Y P K S L S R H V S V R T S(25) of human CIDE-3.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-4316 detects the human CIDE-3 protein in human samples
  • Expected to recognize mouse samples due to 93% sequence homology
  • PA1-4316 has been successfully used in Western blot procedures
  • By Western blot this antibody detects a ∽27 kDa protein representing human CIDE-3 in HepG2 cell lysate
  • The PA1-4316 immunogen is a synthetic peptide corresponding to residues L(10) L Y P K S L S R H V S V R T S(25) of human CIDE-3
  • This antibody shows cross-reactivity to FSP27, which is the mouse homolog of CIDE-3, with a sequence identity of 93%
  • Maintain at 4oC for 3 months or at -20oC for longer periods
  • Avoid repeated freeze-thaw cycles
  • DNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF)
  • DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45)
  • Recently a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified
  • Human CIDE-3 is a novel member of CIDEs
  • There are 2 transcripts, CIDE-3 and CIDE-3alpha, were present in HepG2 and A375 cells
  • Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumours, CIDE-3 may play an important role in prevention of tumorigenesis.