HRD1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA146121-Each-of-1 | In Stock | ₹ 46,146.50 |
PA146121 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,146.50
GST (18%): ₹ 8,306.37
Total Price: ₹ 54,452.87
Antigen
HRD1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SYVN1
Gene Alias
1200010C09Rik; AW211966; C85322; D530017H19Rik; DER3; E3 ubiquitin-protein ligase synoviolin; HMG-coA reductase degradation 1 homolog; Hrd1; HRD1 protein; KIAA1810; MGC40372; RGD1310488; RING-type E3 ubiquitin transferase synoviolin; Synovial apoptosis inhibitor 1; synovial apoptosis inhibitor 1, synoviolin; synoviolin 1; Syvn1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100765313, 74126, 84447
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.0 mg/mL
Formulation
whole serum diluted in PBS with no preservative
Gene Accession No.
Q86TM6, Q9DBY1
Gene Symbols
SYVN1
Immunogen
A synthetic peptide made to an internal portion of the human protein (within residues 300-400). [UniProt Q96PK3]
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Hamster, Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Suggested positive control: 293T, INS-1, and MIN6 cell lysates, antigen standard for SYVN1 (transient overexpression lysate)
- HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress
- Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum
- HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle
- It has been reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its anti-apoptotic effects
- HRD1 contains one ring-type zinc finger.