PA146194

LRRK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA146194-Each-of-1 In Stock ₹ 46,502.50

PA146194 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

LRRK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LRRK2

Gene Alias

4921513O20Rik; 9330188B09Rik; augmented in rheumatoid arthritis 17; AURA17; AW561911; BC 300-268; cI-46; D630001M17Rik; DARDARIN; DKFZp434H2111; FLJ45829; Gm927; leucine rich repeat kinase 2; leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; Lrrk2; LRRK-2; PARK8; RIPK7; ROCO2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

120892, 300160, 66725

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

phosphate, tris citrate with 0.05% sodium azide; pH 7-8

Gene Accession No.

Q5S006, Q5S007

Gene Symbols

LRRK2

Immunogen

A synthetic peptide made to a C-terminal region, within residues 2500-2527 of the human LRRK2 protein, conjugated to KLH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Suggested positive control: human lymphoblasts for IHC, human and mouse brain for Western blot
  • LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain
  • Mutations in LRRK2 have been associated with Parkinson's disease
  • LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain
  • The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.