PA1562

STARD3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1562-Each-of-1 In Stock ₹ 47,926.50

PA1562 - Each of 1

₹ 47,926.50

In Stock

Quantity

1

Base Price: ₹ 47,926.50

GST (18%): ₹ 8,626.77

Total Price: ₹ 56,553.27

Antigen

STARD3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

STARD3

Gene Alias

CAB1; Es64; metastatic lymph node gene 64 protein; metastatic lymph node protein 64; MLN 64; MLN64; Protein CAB1; Protein ES 64; protein MLN 64; StAR related lipid transfer domain containing 3; STARD3; StAR-related lipid transfer (START) domain containing 3; StAR-related lipid transfer domain containing 3; stAR-related lipid transfer protein 3; START domain containing 3; START domain-containing protein 3; steroidogenic acute regulatory protein related

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

363675

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

0

Gene Symbols

STARD3

Immunogen

Recombinant MLN64 protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-562 detects MLN64 from rat tissues
  • PA1-562 has been successfully used in Western blot procedures
  • By Western blot, this antibody detects an ∽53 kDa protein representing MLN64 from rat adrenal gland tissue extracts
  • This antibody also detects an ∽25 kDa protein from rat adrenal gland which may correspond to degradation product
  • PA1-562 antigen is recombinant MLN64 protein
  • The steroidogenic acute regulatory (StAR) protein facilitates the movement of cholesterol from the outer to inner mitochondrial membrane in adrenal and gonadal cells, fostering steroid biosynthesis
  • MLN64 is a 445-amino acid protein of unknown function
  • When 218 amino-terminal residues of MLN64 are deleted, the resulting N-218 MLN64 has 37% amino acid identity with StAR and 50% of StAR's steroidogenic activity in transfected cells
  • Bacterially expressed N-218 MLN64 exerts StAR-like activity to promote the transfer of cholesterol from the outer to inner mitochondrial membrane in vitro
  • The presence of a protease-resistant domain and a protease-sensitive carboxy-terminal domain in N-218 MLN64 is similar to the organization of StAR
  • However, as MLN64 never enters the mitochondria, the protease-resistant domain of MLN64 cannot be a mitochondrial pause-transfer sequence, as has been proposed for StAR.