IP3 Receptor 1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1901-Each-of-1 | In Stock | ₹ 48,282.50 |
PA1901 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,282.50
GST (18%): ₹ 8,690.85
Total Price: ₹ 56,973.35
Antigen
IP3 Receptor 1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Itpr1
Gene Alias
ACV; CLA4; D6Pas2; ENSMUSG00000072853; Gm10429; I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 1,4,5-trisphosphate receptor, type 1; inositol 1,4,5-trisphosphate-binding protein P400; InsP>3<R type I; Insp3r; InsP3R type I; insP3R1; IP3 receptor; IP3 receptor isoform 1; Ip3r; IP-3-R; IP3R 1; IP3R1; Itpr1; Itpr-1; opisthotonus; opt; P400; Pcd6; Pcp1; Pcp-1; PPP1R94; protein PCD-6; protein phosphatase 1, regulatory subunit 94; Purkinje cell protein 1; SCA15; SCA16; SCA29; SI-SIII-SIIA; Type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16438, 25262, 3708, 476548
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Concentration
1.3 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
P11881, P29994, Q14643
Gene Symbols
Itpr1
Immunogen
Synthetic Peptide: N(1829) K K K D D E V D R D A P S R K K A K E(1848)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-901 detects inositol 1,4,5-trisphosphate receptor type-I (IP3R-I) from canine, mouse and rat tissues
- PA1-901 has been successfully used in Western blot, immunohistochemistry, immunofluoresence and immunoprecipitation procedures
- By Western blot, this antibody detects an ∽240 kDa protein representing IP3R-I from rat and mouse brain extract
- Immunohistochemical staining of IP3R-I in rat cerebellum with PA1-901 results in staining of Purkinje cells
- PA1-901 immunizing peptide corresponds to amino acid residues 1829-1848 from human IP3R-I
- This sequence is completely conserved in human, mouse, and rat IP3R-I
- PA1-901 immunizing peptide (Cat
- # PEP-019) is available for use in neutralization and control experiments
- Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate
- Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1
- Plays a role in ER stress-induced apoptosis
- Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.