PA549745

ITGB5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA549745-Each-of-1 In Stock ₹ 52,510.00

PA549745 - Each of 1

₹ 52,510.00

In Stock

Quantity

1

Base Price: ₹ 52,510.00

GST (18%): ₹ 9,451.80

Total Price: ₹ 61,961.80

Antigen

ITGB5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Itgb5

Gene Alias

[b]5; [b]-5; [b]5A; [b]5B; AA475909; AI874634; beta5; beta-5; CD61; ESTM23; FLJ26658; GP3A; GPIIIa; I79_000655; integrin beta 5; integrin beta-5; integrin subunit beta 5; integrin, beta 5; ITGB5; RGD1563276; testis secretory sperm-binding protein Li 217p

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16419, 257645, 3693

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O70309, P18084

Gene Symbols

Itgb5

Immunogen

Synthesized peptide derived from human Integrin beta5.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total Integrin beta 5 protein
  • Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces
  • They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit
  • Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature
  • Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell-surface receptors, they bind ligands with very low affinity
  • Due to their weak individual binding, integrins need to cluster and bind in-groups in order to effectively bind the ECM
  • Integrins bind many different ligands including laminin
  • Each integrin is made up of a large N-terminal extracellular domain that binds the ECM ligand and a small C-terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function.