PA550195

AARS2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550195-Each-of-1 In Stock ₹ 46,502.50

PA550195 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

AARS2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AARS2

Gene Alias

AARS2; AARSL; alanine tRNA ligase 2, mitochondrial (putative); alanine--tRNA ligase, mitochondrial; alanine--tRNA ligase, mitochondrial {ECO:0000255; Alanyl-tRNA synthetase; alanyl-tRNA synthetase {ECO:0000255; alanyl-tRNA synthetase 2, mitochondrial; alanyl-tRNA synthetase 2, mitochondrial (putative); alanyl-tRNA synthetase like; alanyl-tRNA synthetase, mitochondrial; alaRS; alaRS {ECO:0000255; bA444E17.1; COXPD8; Gm89; HAMAP-Rule:MF_03133}; Kiaa1270; LKENP; MTALARS; MT-ALARS; probable alanyl-tRNA synthetase, mitochondrial

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

224805, 57505

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.3 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q14CH7, Q5JTZ9

Gene Symbols

AARS2

Immunogen

Fusion protein corresponding to a region derived from internal residues of human Alanyl-tRNA synthetase 2, mitochondrial

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total AARS2 protein
  • The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family
  • Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids
  • The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA
  • Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8
  • Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala)
  • Also edits incorrectly charged tRNA(Ala) via its editing domain.