PA550246

OAS2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550246-Each-of-1 In Stock ₹ 46,057.50

PA550246 - Each of 1

₹ 46,057.50

In Stock

Quantity

1

Base Price: ₹ 46,057.50

GST (18%): ₹ 8,290.35

Total Price: ₹ 54,347.85

Antigen

OAS2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

OAS2

Gene Alias

(2-5')oligo(A) synthase 2; (2'-5')oligo(A) synthetase 2; 2',5'-oligoadenylate synthetase-like 11; 2,5-oligoadenylate synthetase-like 11; 2'-5' oligoadenylate synthetase 2; 2'-5' oligoadenylate synthetase-like 11; 2-5A synthase 2; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; A synthetase 2; MGC78578; Oas2; Oasl11; p69 OAS / p71 OAS; p69OAS / p71OAS

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

246728, 4939

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.9 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

E9Q9A9, P29728

Gene Symbols

OAS2

Immunogen

Fusion protein corresponding to a region derived from internal residues of human 2'-5'-oligoadenylate synthetase 2, 69/71kDa

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PA550674

--

Img

Thermo Scientific

PA550680

--

Img

Thermo Scientific

PA550286

--

Img

Thermo Scientific

PA550738

--

Img

Thermo Scientific

PA550334

--

Img

Thermo Scientific

PA550344

--

Img

Thermo Scientific

PA550465

--

Img

Thermo Scientific

PA550942

--

Description

  • The antibody detects endogenous levels of total OAS2 protein
  • This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection
  • The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates
  • These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication
  • The three known members of this gene family are located in a cluster on chromosome 12
  • Alternatively spliced transcript variants encoding different isoforms have been described.