PDCD6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550249-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550249 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PDCD6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pdcd6
Gene Alias
Alg2; alg-2; ALG-257; Apoptosis-linked gene 2 protein; Apoptosis-linked gene 2 protein homolog; AV299538; MA-3; PDCD6; PEF1B; PMP41; probable calcium-binding protein ALG-2; programmed cell death 6; programmed cell death protein 6; PS2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10016
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.7 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
O75340
Gene Symbols
Pdcd6
Immunogen
Fusion protein corresponding to a region derived from internal residues of human programmed cell death 6
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total PDCD6 protein
- An increased intracellular Ca2+ concentration induces apoptotic cell death
- Transiently elevated Ca2+ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis
- ALG-2 (for apoptosis-linked gene 2) is a Ca2+ -binding protein that participates in regulatory events occuring late in the apoptotic program and where several death signals converge
- ALG-2 is a protein expressed in normal brain, and to a greater extent in ischemic brain
- The ALG-2 protein contains five EF-hand-like motifs and shares homology with members of the penta EF-hand family, which includes Calpain small subunits sorcin and Grancalcin.