PA550442

LRRC15 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550442-Each-of-1 In Stock ₹ 46,057.50

PA550442 - Each of 1

₹ 46,057.50

In Stock

Quantity

1

Base Price: ₹ 46,057.50

GST (18%): ₹ 8,290.35

Total Price: ₹ 54,347.85

Antigen

LRRC15

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LRRC15

Gene Alias

5430427N11Rik; hLib; leucine rich repeat containing 15; Leucine-rich repeat protein induced by amyloid-beta; leucine-rich repeat protein induced by beta amyloid; leucine-rich repeat protein induced by beta-amyloid; leucine-rich repeat protein induced by beta-amyloid homolog; Leucine-rich repeat-containing protein 15; LIB; Lrrc15; rLib

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

131578

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

0.4 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q8TF66

Gene Symbols

LRRC15

Immunogen

Fusion protein corresponding to a region derived from internal residues of human leucine rich repeat containing 15

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total LRRC15 protein
  • Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions
  • The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions
  • LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development
  • Several human diseases are associated with mutations in genes encoding LRR-containing proteins
  • The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions
  • LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma
  • It is also associated with the pathogenesis of Alzheimer's disease.