PA550730

PLCL1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550730-Each-of-1 In Stock ₹ 48,104.50

PA550730 - Each of 1

₹ 48,104.50

In Stock

Quantity

1

Base Price: ₹ 48,104.50

GST (18%): ₹ 8,658.81

Total Price: ₹ 56,763.31

Antigen

PLCL1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PLCL1

Gene Alias

130kDa-Ins(1,4,5)P3 binding protein; C230017K02Rik; inactive phospholipase C-like protein 1; p130; phospholipase C like 1; phospholipase C related, but catalytically inactive protein; phospholipase C, epsilon; phospholipase C, eta 2 pseudogene; phospholipase C-deleted in lung carcinoma; phospholipase C-like 1; phospholipase C-related but catalytically inactive protein; PLCE; PLCL; PLC-L; PLCL1; PLC-L1; PLDL1; PPP1R127; PRIP; PRIP1; PRIP-1; protein phosphatase 1, regulatory subunit 127

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5334

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

2.8 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q15111

Gene Symbols

PLCL1

Immunogen

Synthetic peptide corresponding to residues near the N terminal of human phospholipase C-like 1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total PLCL1 protein
  • Involved in an inositol phospholipid-based intracellular signaling cascade
  • Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol
  • Component in the phospho-dependent endocytosis process of GABA A receptor
  • Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition
  • Its aberrant expression could contribute to the genesis and progression of lung carcinoma
  • Acts as a inhibitor of PPP1C.