PA551153

DUSP11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA551153-Each-of-1 In Stock ₹ 46,502.50

PA551153 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

DUSP11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DUSP11

Gene Alias

2010300F21Rik; AI481497; dual specificity phosphatase 11; dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); dual specificity protein phosphatase 11; DUSP11; Phosphatase that interacts with RNA/RNP complex 1; PIR1; RNA/RNP complex 1-interacting; RNA/RNP complex-1-interacting phosphatase; RNA/RNP complex-1-interacting phosphatase-like protein; RNA/RNP complex-interacting phosphatase; serine/threonine specific protein phosphatase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8446

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1.3 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

O75319

Gene Symbols

DUSP11

Immunogen

Full length fusion protein of human DUSP11

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total DUSP11 protein
  • DUSP11 (dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)) is a member of the dual specificity protein phosphatase subfamily
  • These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues
  • They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation
  • Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli
  • This gene product is localized to the nucleus, and is novel in that it binds directly to RNA and splicing factors, and thus suggested to participate in nuclear mRNA metabolism.