PA550823

LONP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550823-Each-of-1 In Stock ₹ 44,633.50

PA550823 - Each of 1

₹ 44,633.50

In Stock

Quantity

1

Base Price: ₹ 44,633.50

GST (18%): ₹ 8,034.03

Total Price: ₹ 52,667.53

Antigen

LONP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LONP1

Gene Alias

1200017E13Rik; CODASS; h LonHS; HAMAP-Rule:MF_03120}; hLON; hLON ATP-dependent protease; Lon; lon peptidase 1, mitochondrial; lon protease homolog, mitochondrial; lon protease homolog, mitochondrial {ECO:0000255; Lon protease-like protein; lon protease-like protein {ECO:0000255; LONHs; LONP; LONP {ECO:0000255; LONP1; Mitochondrial ATP-dependent protease Lon; mitochondrial ATP-dependent protease Lon {ECO:0000255; mitochondrial lon protease-like protein; PIM1; protease, serine, 15; Prss15; Serine protease 15; serine protease 15 {ECO:0000255

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

74142, 9361

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.6 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P36776, Q8CGK3

Gene Symbols

LONP1

Immunogen

Synthetic peptide corresponding to residues near the C terminal of human lon peptidase 1, mitochondrial

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total LONP1 protein
  • This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases
  • This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix
  • It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome
  • Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia
  • Alternatively spliced transcript variants have been found for this gene.